Job Description

Company Description

OHR uses primordial chemistry and synthetic biology to fashion strategic chemicals. Our technology enables the creation of carbon chains of deterministic length without cells, co-factors, or typical oil contaminants. With a core value of sustainability, OHR is focused on disrupting the petroleum industry through innovative solutions.

Role Description

Ohr Synbiosis is seeking an experienced Synthetic Organic and/or Process Development R&D Chemist in it's San Diego R&D lab. The candidate will spearhead chemical reaction discovery and chemical process development to convert biologically-derived intermediates into sustainable, industrial chemical products. The candidate will need to perform both in lab experiments and detailed dry-lab planning.

Responsibilities

• Design and demonstrate novel multistep chemical syntheses to produce Ohr’s target compounds.
• Perform discovery reactions with full characterization of all byproducts to quantify reaction performance.
• Implement HPLC, GC, MS, TGA, and other relevant analytical techniques to determine reaction products and byproducts.
• Perform reaction optimization DBTL cycles to optimize: conversion, yield, solvent selection, operating conditions, and product recovery.
• Identify and apply heterogeneous catalysts for diverse reactions.
• Identify appropriate equipment needed for Ohr to expand its R&D and Pilot Lab Chemistry footprint.
• Perform heterogeneous hydrogenation and hydrodeoxygenation reaction discovery and process development.
• Identify and evaluate appropriate industrial protection groups amendable to massive-scale production.
• Perform aromatic modification reaction discovery and development.
• Evaluate and implement chemical process product purification techniques including crystallization, liquid-liquid extraction, precipitation, filtration, and distillation.
• Scale product recovery techniques to Pilot Lab unit operations.
• Leverage knowledge of organic chemistry to design multistep synthetic routes that maintain carbon skeletons and stabilize molecules.
• Apply knowledge of both batch and flow chemistry to develop novel reactions and optimize conditions.
• Lead interactions with CROs, in parallel with in-house experiments, to rapidly develop chemical processes and to gather additional analytical datasets.
• Exemplify excellence in lab safety and chemical hygiene practices.
• Strengthen and expand both chemistry data and project management to streamline communication in Ohr’s R&D team.
• Organize, present, and share data, challenges, questions, and strategies with Ohr’s global team.

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